Last Friday, the domestic rutile and anatase titanium dioxide new single price was stable, and the overall transaction focus of the market moved up. Titanium dioxide factory work normally, part of the output of early orders, the spot supply has increased accordingly; And buyers still have inventory digestion, the current mentality turned to wait-and-see. The volume of new orders in the market is limited.The key factors affecting the current market price change1.
Fig. 3. Cell survival measured on samples of MSSA with bare and functionalized P25TiO2NPs after 6 h of irradiation. A: P25TiO2NPs, B:vitaminB2@P25TiO2NPs, C: vitaminC@P25TiO2NPs in concentrations of 0.2 μg/mL (red) and 0.2 mg/mL (blue). p <0.05.
What titanium dioxide is really emblematic of ... is the failure of FDA to look back at these old decisions and ask whether its decisions that were made in this case ... 56 years ago (in the 1966 approval) still hold up, he said.

Stability and darkening
As a food additive, titanium dioxide and its nanoparticles in particular have been associated with DNA damage and cell mutations, which in turn, have potential to cause cancer. When used as a food coloring, it is known as E171.
Lithopone


SYNONYMES (LISTE NON EXHAUSTIVE)
TiO2 has been well accepted in the food industry and can be found as the E171 additive in various food products, mainly for whitening and texture. It is present in some cottage and Mozzarella cheeses, horseradish cream and sauces, lemon curd, and in low-fat products such as skimmed milk and ice-cream. Even if the product is labelled as containing E171, no information is usually given about the quantity, particle size and particle structure. FDA claims that TiO2 may be safely used as a colour additive for colouring foods in quantities up to 1 % by weight of the food. Interestingly, TiO2 is frequently declared as a “natural colouring agent” and is therefore well accepted by consumers.
After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body, Maged Younes, chair of the European Food Safety Authority's expert Panel on Food Additives and Flavourings, said in a May 2021 statement.
The calcined product obtained by the ordinary zinc-barium white preparation method is beaten into a slurry, which is then surface-treated with sodium silicate, aluminum sulfate or sodium aluminate and surfactant, and then filtered, washed, dried and pulverized. Can.
For a review published in 2023 in the journal Environmental Pollution, researchers examined E171 as a possible factor promoting obesity-related metabolic disorders. Because gut microbiota play an important role in immune function maintenance and development, and because titanium dioxide as a food additive has been shown to alter gut microbiota, researchers wanted to review “the dysregulations along the gut microbiota-immune system axis after oral TiO2 exposure compared to those reported in obese or diabetic patients, and to highlight potential mechanisms by which foodborne TiO2 nanoparticles may increase the susceptibility to develop obesity-related metabolic disorders.” The study authors discovered recurrent changes in the gut microbiota composition when exposed to titanium dioxide nanoparticles, with an imbalance of intestinal symbiotic microbiota. These changes and imbalances were also reported and played a role in the development of obesity, the authors wrote. This highlights “foodborne TiO2 nanoparticles as an endocrine disruptor-like chemical promoting obesity-related disorders,” the authors concluded.