The updated evaluation revises the outcome of EFSA’s previous assessment published in 2016, which highlighted the need for more research to fill data gaps.  

Scattering Power of TiO2 and Pigment Volume Concentration

Calcium carbonate (CaCO3) and titanium dioxide (TiO2) are two widely used industrial materials with various applications. In this article, we will discuss the importance of CaCO3 and TiO2 in manufacturing processes and their impact on the global economy.

Titanium dioxide in sunscreen

Titanium is a metal element found naturally in the environment. When it's exposed to oxygen in the air, it forms titanium oxides that are contained in many minerals, sands, soils, and dusts.

Since then, there has been a few animal studies suggesting titanium dioxide is connected to cancer. A 2017 study in Scientific Reports, for instance, found that rats with titanium dioxide in their diet had impaired immune systems, which could contribute to autoimmune diseases and colorectal cancer.

Recently, Yanagisawa et al. reported that the transdermal exposure (mimicking skin-barrier dysfunction or defect) of NC/Nga mice to TiO₂ NPs (15, 50, or 100 nm), in combination with allergen, aggravated atopic dermatitis-like lesions through a T-helper type 2 (Th2) dominant immune response. The study also indicated that TiO₂ NPs can play a role in the initiation and/or progression of skin diseases, since histamine was released, even in the absence of allergen.

In addition to its strength and UV resistance, nano titanium dioxide also has excellent optical properties. This makes it an ideal material for use in pigments and coatings, as it can help create vibrant colors and enhance the appearance of a wide range of products. Our nano titanium dioxide products are carefully formulated to ensure that they provide the best possible optical properties, so customers can achieve the look they desire.

Asia

Available studies in humans and postmortem analysis of tissues suggested that the oral bioavailability of titanium dioxide in humans is very low. JECFA noted that there are currently no epidemiological studies that allow any conclusions to be drawn with respect to an association between dietary exposure titanium dioxide and human health effects.

Total zinc and barium sulphate

In a 2022 study published in the Journal of Hazardous Materials, scientists wanted to examine the effects of titanium dioxide as a food additive on atherosclerosis in mice. (Atherosclerosis refers to a hardening of the arteries.) Researchers fed mice 40 mg/kg of the food additive every day for 4 months, and found that it not only altered gut microbiota but also led to a significantly increased atherosclerotic lesion area, especially in animals that consumed a high-choline western diet (HCD).