Titanium dioxide in sunscreen

Prof. Matthew Wright, chair of EFSA’s working group on E171, noted: “Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods we could not rule out a concern for genotoxicity and consequently we could not establish a safe level for daily intake of the food additive.”

Because of their small size, nanoparticles may have unique physical and chemical properties. These properties may cause them to interact with living systems differently than larger materials with the same chemical composition (also known as bulk materials).

The global Lithopone market was valued at $169.8 million in 2019, and is projected to reach $218.6 million by 2027, growing at a CAGR of 3.30% from 2020 to 2027.

While the anatase titanium dioxide market is robust, it faces challenges such as regulatory compliance and environmental concerns related to extraction and processing. Manufacturers are increasingly adopting sustainable practices, focusing on recycling materials and minimizing waste in production processes. Innovations in nanotechnology are also leading to the development of more efficient and eco-friendly synthesis methods that can further enhance the properties of anatase TiO2.

Lithopone in fillers, adhesives, joints and sealants

The aim of this work was to examine particularly the Degussa P25 titanium dioxide nanoparticles (P25TiO₂NPs) because they are among the most employed ones in cosmetics. In fact, all kinds of titanium dioxide nanoparticles (TiO₂NPs) have gained widespread commercialization over recent decades. This white pigment (TiO₂NPs) is used in a broad range of applications, including food, personal care products (toothpaste, lotions, sunscreens, face creams), drugs, plastics, ceramics, and paints. The original source is abundant in Earth as a chemically inert amphoteric oxide, which is thermally stable, corrosion-resistant, and water-insoluble. This oxide is found in three different forms: rutile (the most stable and substantial form), brookite (rhombohedral), and anatase (tetragonal as rutile), of these, both rutile and anatase are of significant commercial importance in a wide range of applications [3]. Additionally, the nano-sized oxide exhibits interesting physical properties, one of them is the ability to act as semiconducting material under UV exposure. In fact, TiO₂NPs are the most well-known and useful photocatalytic material, because of their relatively low price and photo-stability [4]. Although, this photoactivity could also cause undesired molecular damage in biological tissues and needs to be urgently assessed, due to their worldwide use. However, not all nanosized titanium dioxide have the same behavior. In 2007, Rampaul A and Parkin I questioned: “whether the anatase/rutile crystal form of titanium dioxide with an organosilane or dimethicone coat, a common titania type identified in sunscreens, is appropriate to use in sunscreen lotions” [5]. They also suggested that with further study, other types of functionalized titanium dioxide could potentially be safer alternatives. Later, Damiani found that the anatase form of TiO₂NPs was the more photoactive one, and stated that it should be avoided for sunscreen formulations, in agreement with Barker and Branch (2008) [6,7].

Specific gravity:

In addition to sunscreen, titanium IV oxide is also used in the production of paints. Titanium dioxide is a popular pigment in the paint industry because of its brightness and opacity. It provides excellent coverage and durability, making it an ideal choice for exterior and interior paints. Titanium dioxide is often used in white paints, but it can also be used to create a wide range of colors by mixing it with other pigments.