Though the regulated use of titanium dioxide in food products is legal in the U.S. and Canada, it's banned in some other countries, notably throughout Europe. In May 2021, the European Food Safety Authority announced that titanium dioxide can no longer be considered safe as a food additive.

In its 2016 opinion, the ANS Panel recommended new studies be carried out to fill the gaps on possible effects on the reproductive system, which could enable them to set an Acceptable Daily Intake (ADI ). Uncertainty around the characterisation of the material used as the food additive (E 171) was also highlighted, in particular with respect to particle size and particle size distribution of titanium dioxide used as E 171.   

Fluorine Chemical, Lithopone 30% CAS No. 1345-05-7, white powder, relative density: 4.136 ~ 4.39 g / mL, insoluble in water. It is a mixture of zinc sulfide and barium sulfate. Inorganic white pigment, widely used in plastics such as polyolefin, vinyl resin, ABS resin, polystyrene, polycarbonate, nylon and polyoxymethylene, and white pigments of paints and inks. It is less effective in polyurethane and amino resins and less suitable in fluoroplastics. It is also used for coloring of rubber products, paper, varnish, tarpaulin, leather, watercolor paint, paper, enamel, and the like. Used as a binder in the production of electric beads.

It's also added directly to food; mainly for coloring, but also as a thickener and to keep some powdered food, like confectioner's sugar, from clumping.   

New Safety Rulings & Regulations

Rutile titanium dioxide R-996, white powder, insoluble in water, non-physiological toxicity, stable chemical properties, surface coated with silicon, aluminum, zirconium and organic treatment has excellent pigment performance, whiteness, brightness, good gloss; Strong hiding power, achromatic power and fluidity Rutile titanium dioxide, white powder, insoluble in water, non-physiological toxicity, stable chemical properties, excellent pigment performance after the surface is coated with silicon, aluminum, zirconium and organically treated, whiteness , Brightness, good gloss, hiding power, achromatic power and fluidity are strong, with excellent weather resistance and anti-powder properties.

Assessment of biocompatibility

Titanium dioxide is used in the production of paper and textiles to improve whiteness, brightness, opacity and durability. It’s often used in fabrics, yarns, paper and other fibers.