As many of you know, I try to bake all of my own gluten-free goods.
Ophthalmic Solutions:
Is it safe?: In an FDA study with rats, there were no significant toxic effects other than growth retardation once HPMC reached levels of 20 to 30% of the rats’ diet. This study noted that growth retardation may be contributed to malnutrition and not the amount of HPMC. In another study, rabbits were injected with 2% HPMC for over a month and there were no observations of toxicity or irritation. Overall, the FDA sees it as a non-toxic and non-irritating inactive ingredient that is safe for human use and consumption.
Answer: HPMC in the application of putty powder, thickening, water retention and construction of three roles. Thickening: Cellulose can be thickened to suspension, so that the solution to maintain uniform up and down the role of the same, anti-hanging. Water retention: Make putty powder dry slowly, assist ash calcium reaction under the action of water. Construction: cellulose has lubricating effect, can make putty powder has good construction property. HPMC does not participate in any chemical reactions, but only plays an auxiliary role. Putty powder and water, on the wall, is a chemical reaction, because of the formation of new substances, the putty powder on the wall off the wall, ground into powder and then use, will not work, because a new substance (calcium carbonate) has been formed. The main components of ash calcium powder are: Ca(OH)2, CaO and a small amount of CaCO3 mixture,
CaO+H2O=Ca(OH)2 - Ca(OH)2+CO2=CaCO3↓+H2O Ash calcium generates calcium carbonate under the action of CO2 in water and air, while HPMC only holds water to assist ash calcium to react better, and itself does not participate in any reaction.
2)The viscosity of Hydroxypropyl Methylcellulose is influenced by its molecular weight, with higher molecular weight leading to higher viscosity. Temperature also affects its viscosity, with viscosity decreasing as temperature rises. However, the impact of temperature on viscosity is lower compared to Methyl Cellulose. Its solution is stable when stored at room temperature.
(8) Safety and regulatory considerations:
Hydroxypropyl methylcellulose has a generally recognized safety profile and is considered safe for consumption when used in accordance with regulatory guidelines. It is approved by regulatory agencies in several countries for use in pharmaceuticals and dietary supplements.

Hydroxypropyl methyl cellulose is intended to be used as a technological additive (functional group: emulsifier, stabiliser, thickener, gelling agent and binder) in feedingstuffs for all animal species, with no recommendation of a minimum or maximum content.