The safety of the food additive E 171 was re-evaluated by the EFSA ANS Panel in 2016 in the frame of Regulation (EU) No 257/2010, as part of the re-evaluation programme for food additives authorised in the EU before 20 January 2009.  

A legal additive in the United States, titanium dioxide is used in everything from food to consumer goods and the U.S. Food and Drug Administration says regulated use of the product as a color additive in food is safe within certain restrictions.

Le Lithopone Alcalin est un pigment blanc formé par le mélange intime en précipitation simultanée de sulfure de zinc et de Sulfate de Baryum. Le lithopone dit normal renferme 29.5% de ZnS et 70.5% de BasSO4 et renferme un peu d'Oxyde de Zinc.

Nanoparticles

Still, you may wonder whether it’s safe for consumption.

In conclusion, the CaCO3 and TiO2 factory plays a vital role in supporting industrial and economic development by producing high-quality materials for a wide range of applications. The continued growth of industries such as construction, agriculture, and manufacturing relies on the availability of CaCO3 and TiO2 from reliable sources like the factory. As technology advances and demand increases, the factory will continue to innovate and expand its production capacity to meet the needs of a rapidly changing world.

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In a review published in 2022 in the journal Archives of Toxicology, researchers found that the ingestion of E171 is a “a definite health risk for consumers and their progeny.” After reviewing dozens of in vivo, ex vivo and in vitro studies on the toxicity of E171, the researchers wrote that two facts must be noted: “First, reprotoxicity studies show that animals of both sexes are impacted by the toxicity of these nanoparticles, underlining the importance of conducting in vivo studies using both male and female animals. Second, human exposure begins in utero via maternal-fetal transfer and continues after birth by breastfeeding. Children are then chronically re-exposed due to their food preferences. To be relevant to the human in vivo situation, experimental studies should therefore consider nanoparticle exposure with respect to the age or life period of the studied population.”