Titanium dioxide manufacturer: Lomon 

Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods our scientists could not rule out a concern for genotoxicity and consequently they could not establish a safe level for daily intake of TiO₂ as a food additive.

Recent policy changes in regard to titanium dioxide

Variations of titanium dioxide are added to enhance the whiteness of paint, plastics, and paper products, though these variations differ from the food-grade ones for things we eat (1Trusted Source, 2Trusted Source).

In response to the allegations, Justin Comes, vice president of research and development at Mars Wrigley North America, told Health that safety is of paramount importance to Mars Wrigley. While we do not comment on pending litigation, all Mars Wrigley ingredients are safe and manufactured in compliance with strict quality and safety requirements established by food safety regulators, including the FDA.

Additionally, the growing emphasis on sustainability within the automotive industry influences the demand for environmentally friendly tire production methods. TiO2, being a non-toxic and eco-friendly compound, aligns with these sustainability goals, making it an attractive option for manufacturers looking to reduce their environmental footprint.

ROS were detected through the colorimetric assay employing the nitro-blue tetrazolium salt (NBT salt) by reading the absorbance of the reduced blue molecule.

Bluescope Steel now specifically mention sunscreen & titanium dioxide use in their warranty so they no longer have to pay out for the damage caused by a little bit of transferred sunscreen residue.

The following aspects have been covered in the lithopone manufacturing plant report:

If you want to avoid titanium dioxide, read labels carefully and stick to minimally processed whole foods.

Titanium dioxide nanoparticles may accumulate and cause DNA damage

Overall, the Food Directorate's comprehensive review of the available science of TiO₂ as a food additive showed:

Lithopone has therefore traditionally been used in stoppers and putties, jointing compounds and sealing compounds, primers and undercoats and in road-marking paints.

if you compare the levels—which went as high as 50,000 milligrams/killigrams per day— to what humans are actually exposed to, we're talking orders of magnitude. It was a huge amount, Norbert Kaminski, PhD, a professor of pharmacology & toxicology and director of the Center for Research on Ingredient Safety at Michigan State University told Health.

Assessment of biocompatibility in eukaryotic cells

When asked about the recent Skittles lawsuit, the FDA said the agency does not comment on pending litigation.