If you are taking medications, consult your doctor before considering starting curcumin supplements. In vitro studies have shown that curcumin increases the risk of bleeding in patients taking diluents at the same time, so any possible drug interactions or concerns must be discussed with your doctor. There have also been reports of curcumin powder causing allergic reaction to contact, such as itching or rash immediately after contact.

The primary distinction between crushed red pepper and paprika lies in their flavor profiles and heat levels:

Chipotle powder is probably the best smoked paprika substitute on your spice rack. Like the original ingredient, this replacement is also considered mildly spicy with a heat level that ranges from 2,500 to 8,000 Scoville Heat Unit (SHU) on the Scoville Scale. Made from smoked dried jalapeño peppers, this spice is also known for its remarkable smoky and earthy taste — the result of the smoking process. Its bright red color also closely resembles paprika. All things considered, the chipotle powder is a fantastic backup for smoky dishes rather than spicy recipes. 

Sometimes you may find yourself missing a key spice in the middle of cooking. Don’t worry—there are several clever substitutions for common red pepper spices that can save your dish without sacrificing flavor. Remember, though, that when substituting spices, it’s good to start with a conservative amount and adjust to taste.