Why does the exposure route matter, and what's the risk?

Worldwide Lithopone Industry to 2027 - Use of Lithopone in the Paints & Coatings Industry is Driving Growth - ResearchAndMarkets.com
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In food products, E171 is not a singular ingredient; it’s always combined with other ingredients (e.g., proteins and fats) in the food product. Digesting food is a slow process for the body compared to drinking a beverage, which passes much faster through the body.
You can find more information about EFSA’s work in the area of food additives on our website
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Restraint
In sunscreen, titanium dioxide is used as a barrier to keep the sun's ultraviolet (UV) rays from damaging your skin. It's processed into much smaller particles than what goes into food, called nanoparticles. In this form, it becomes transparent, and also absorbs UV light so it doesn't reach your skin.
6.0-8.0

pH-value
Application:
1. Due to its rheological and optical properties, Lithopone offers technical and economic advantages wherever organic and inorganic resin systems need to be relatively highly pigmented for specific applications. Lithopone has therefore traditionally been used in putties, mastics, jointing and sealing compounds, primers, undercoats and marking paints. In powder coatings it is possible to replace TiO2 partially, very economically.
2. The low Mohs' hardness of Lithopone leads to low abrasiveness in comparison with TiO2.
3. Lithopone 30 % (= 30% zinc sulfide share) is proven to be of particular use as a TiO2 Substitute in thermoplastic masterbatches. Even at very high pigment loadings it disperses easily. A masterbatch containing 50 % TiO2 and 25 % Lithopone 30 % DS has the same hiding power as one containing 60 %TiO2. Cost savings are strongly related to the price ratio of Lithopone and TiO2 and the price of for example polyethylene or polypropylene.
4. The Lithopone batch has a much higher extrusion rate too. Furthermore the impact strength of many thermoplastics such as PP and ABS can be noticeably improved by using Lithopone as a TiO2 substitute. Generally spoken, Lithopone can be used at loadings up to 80 % by weight without causing polymer breakdown
Oil absorption, g/ 100g
Basic Information:
Above 20%, it is recommended to replace 1 kg TiO2 with 1.3 kg of lithopone supplier 30%.
Un pigment apparenté, mais où le sulfate de baryum est remplacé par du sulfate de calcium, prend le nom de « sulphopone »