In ruminants, cellulose is first hydrolysed by ruminal microorganisms into cellobiose, then is fermented to pyruvate and finally volatile fatty acids. The changes of forage to concentrate ratios in the diet significantly affect the number and type of rumen microorganisms and then affect the end products of fermentation. Moreover, the extent of cellulose digestion is a compromise between the rate of hydrolysis and the retention time in the rumen related to the particle size of the forage. The intrinsic digestibility of cellulose depends on the origin and treatment of the forage. As far as cellulose is associated to lignin, hemicelluloses and cutin in natural forages, a wide range of digestibility is observed (30 to 90%). Crystallinity of cellulose decreases the rate but not the extent of digestibility that may reach 80% (Van Soest, 1994).
2. The role of hydroxypropyl methylcellulose in vitamins:
HPMC was first discovered in 1891, but it wasn't until 1951 that the pharmaceutical industry started using HPMC in its products. It was recognized as a safe drug delivery system when it was used with other drugs that were poorly absorbed or eliminated from the body. In 1967, HPMC was approved by the FDA for use in over-the-counter medicines such as cough syrups and throat sprays, as well as topical creams and gels for the treatment of minor burns and skin conditions such as eczema or psoriasis. In today's world, many consumers are using natural remedies on their skin or seeking alternative treatments for chronic diseases such as diabetes, heart disease, and high blood pressure.
Commercial production



Einsatz von HPMC
