What is an exposure route?

In 2019, EFSA published a statement on the review of the risk related to the exposure to food additive titanium dioxide (E171) performed by the French Agency for Food, Environment and Occupational Health Safety (ANSES). In its statement, EFSA highlighted that the ANSES opinion reiterated the uncertainties and data gaps previously identified by EFSA and did not present findings that invalidated the Authority’s previous conclusions on the safety of titanium dioxide.
Plus, titanium dioxide is chemically inert, meaning it won't react with other substances in the paint. This stability ensures that the paint retains its original color and properties over time, preventing discolouration and degradation. Using titanium dioxide as an ingredient, the paint can withstand harsh weather conditions and prevent flaking, peeling or chalking. This exceptional durability makes it ideal for interior and exterior walls, ensuring a long-lasting and beautiful finish.
1. 296 to 1.357 g/cm3 is obtained. The reaction solution is subjected to pressure filtration through a plate frame to obtain a cake-like lithopone powder having a water content of not more than 45%. The mixture is calcined in a dry roaster to change the crystal form of the lithopone, and then acid-washed with sulfuric acid at a temperature of 80 °C. Finally, it is washed with water, reinforced with coloring agent, pressure filtration, drying and milling.
Tint reducing power, compared with standard samples
Moreover, the gravimetric method's inherent accuracy makes it a preferred choice for regulatory compliance. Many manufacturing processes are subject to stringent quality regulations, and having reliable methods for determining material composition is fundamental to meeting these standards. Accurate gravimetric analysis assists manufacturers in minimizing waste, optimizing formulations, and ensuring that end products are both effective and safe.
What titanium dioxide is really emblematic of ... is the failure of FDA to look back at these old decisions and ask whether its decisions that were made in this case ... 56 years ago (in the 1966 approval) still hold up, he said.

Lithopone B301
R-5568:
Specification: